Awaiting product image

CDT-TRASFERRIN, CARBOHYDRATEDEFICIENT -Alcohol

$79.95

Quest Diagnostics Laboratory-CDT. alcohol Test-TRASFERRIN, CARBOHYDRATEDEFICIENT Carbohydrate deficient transferrin (CDT) has proven be more useful than most available biochemical tests for alcohol abuse in people. Elevated levels of CDT are…

Please enter -ID Number -Driver’s License Number or Last 4 of SSN
Please enter the first name of the person being tested
Please enter the first letter of middle name of the person being tested (if he/she has a middle name)
Please enter the Last (or Family name) of the person being tested
Please enter the phone number of the person being tested
Please enter the zip code or City and State where you would like the specimen collected. We use this information to find the collection site that is most convenient to you.

SKU: QNAT-YTZ16985 Category:

Description

Quest Diagnostics Laboratory-CDT. alcohol Test-TRASFERRIN, CARBOHYDRATEDEFICIENT

Carbohydrate deficient transferrin (CDT) has proven be more useful than most available biochemical tests for alcohol abuse in people.

Elevated levels of CDT are sugges  of recent alcohol abuse, particularly when these findings are corroborated with measured elevation of other liver-associated enzymes. Some of the uses of CDT include long term monitoring for early detection of relapse drinking during medical treatment, permitting early intervention.2 It may also aid in the assessment for reinstating driver licenses or in identifying chronic alcoholics among traumatized patients.3

 

 

                 
         
        

Test Substance Clinical Significance

Transferrin, Carbohydrate-deficient (Alcohol Use)

– Heavy alcohol use (defined as >4 or 5 beverages per day for two weeks or more) is commonly associated with elevated CDT levels as are certain liver diseases such as primary biliary cirrhosis and chronic active hepatitis and in some patients with genetic D variants of transferrin.

    
       

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Serum samples must be fully coagulated, centrifuged within 1 hour of collection, and must not contain any particles or traces of fibrin after centrifugation. Transfer serum to a clean, plastic, screw-cap vial.

    
         
       
          
          
          
           
          
       

 

From a structural point of view , transferrin is a polypeptide with two N-linked polysaccharide chains, branched with sialic acid residues. According to the level of sialylation, there are various forms of transferrin, tetrasialotransferrin being predominant. The proportion of transferrin with zero, one or two sialic acid chains increases with alcohol consumption but also in the carbohydrate deficient glycoprotein syndrome, leading to the so-called carbohydrate deficient transferrin.