Awaiting product image

LabCorp Carbohydrate-deficient Transferrin (CDT), Adult

$159.00

Please note that this blood test is intended for evaluation of alcohol abuse. CDT measurement is very useful in identifying alcohol consumption that may be considered abusive. Abusive alcohol consumption is defined as consumption of 40mL of…

Please enter -ID Number -Driver’s License Number or Last 4 of SSN
Please enter the first name of the person being tested
Please enter the first letter of middle name of the person being tested (if he/she has a middle name)
Please enter the Last (or Family name) of the person being tested
Please enter the phone number of the person being tested
Please enter the zip code or City and State where you would like the specimen collected. We use this information to find the collection site that is most convenient to you.

SKU: LCBLD-XSWZ123211 Category:

Description

Please note that this blood test  is intended for evaluation of alcohol abuse. CDT measurement is very useful in identifying alcohol consumption that may be considered abusive. Abusive alcohol consumption is  defined  as consumption of  40mL of Alcohol (Ethanol) per day for at least two weeks. CDT levels decline and level off to normal levels in a few weeks after alcohol intake is stopped

 


Other names:
  • Diasialotransferrin
  • Transferrin Isoforms

 

 

 

 

CDT Test reference levels:

• Normal: <1.4%

• Inconclusive: 1.4% to 1.6%

• Elevated: >1.6%

 

Collection:

Serum should be separated from cells within two hours of venipuncture. Send serum frozen in a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

 Serum, frozen

 

CDT testing can be an effective tool for the early diagnosis of chronic alcohol misuse, for the detection of patients addicted to alcohol, and for the follow-up of treatment and diagnosis of alcohol relapse.

CDT quantitation is useful in detecting abusive alcohol consumption (defined as ethanol consumption >40 mL per day for at least two weeks) and a more specific marker for alcohol exposure than other available markers, such as γ-glutamyl transferase (GGT). It enables early detection of alcohol misuses and follow-up of alcoholic patients.

On stopping alcohol consumption, the CDT level goes back to normal after two to four weeks. If the patient starts drinking after withdrawal, CDT increases in a few days.

Transferrin is an 80-kDa serum glycoprotein produced by the liver. Its function is to carry iron around an organism mediated by iron-binding properties. Transferrin comprises a single polypeptide chain with two polysaccharide chains ended by a sialic acid residue. There are several isoforms of human transferrin with different levels of sialylation. Carbohydrate-deficient transferrin (CDT), defined by 2 sialo and 0 sialo isoforms, is a marker of chronic alcohol abuse.